Targeted Protein Degradation
Curated intelligence for the fastest-moving modality in drug discovery.
From PROTACs and molecular glues to LYTACs and next-generation degraders, we deliver expertly curated degrader datasets, ternary complex insights, and E3-ligase intelligence that turn early exploration into confident SAR decisions.
What we do
for your team.
Degrader discovery moves faster than the literature can keep up. We continuously curate published and patent-disclosed degraders, normalized, annotated, and linked to ternary structural context so your teams can act on the full landscape, not a fragment of it.
Our informatics stack fuses medicinal chemistry, structural biology, and proteomics readouts, giving you a single, decision-ready view of degrader SAR across targets, E3 ligases, and chemotypes.
- Comprehensive TPD SAR databases across PROTACs, molecular glues & LYTACs
- Ternary complex prediction, scoring & structural annotation
- E3 ligase–substrate specificity intelligence and ligand libraries
- Linker chemistry design & warhead–POI matchmaking
- Proteomics-based degradation profiling and selectivity readouts
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Prioritized hit lists ranked by predicted degradation efficacy
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Selectivity maps across the expanding E3 ligase landscape
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Reproducible pipelines that plug into your existing chemistry stack